RNA interference-mediated secretory clusterin gene silencing inhibits proliferation and promotes apoptosis of human non-small cell lung cancer cells.

Yan, Yufeng; Luo, Kai; Zhang, Huiqin; Chai, Weiran

doi:10.5754/hge11801

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RNA interference-mediated secretory clusterin gene silencing inhibits proliferation and promotes apoptosis of human non-small cell lung cancer cells.

Shared by NobleBlocks on Sep 7, 2026 • 08:16 PM UTC

Authors:

Yufeng Yan

Kai Luo

Huiqin Zhang

Abstract

BACKGROUND/AIMS: Non-small cell lung cancer (NSCLC) constitutes around 85% of lung cancer cases and is frequently beyond surgical intervention. METHODOLOGY: Secretory clusterin (sCLU) is found in diverse types of human cancers and is unregulated in a variety of cell lines in response to stress, and ...

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