Integrative Analyses of Uterine Transcriptome and MicroRNAome Reveal Compromised LIF-STAT3 Signaling and Progesterone Response in the Endometrium of Patients with Recurrent/Repeated Implantation Failure (RIF)

Choi, Youngsok; Ryun Kim, Hye; Jin Lim, Eun; Park, Miseon; Ah Yoon, Jung; Sun Kim, Yeon; Kyung Kim, Eun; Shin, Jieun; Hyang Kim, Ji; Kwon, Hwang; Song, Haengseok; Choi, Dong‐Hee

doi:10.1371/journal.pone.0157696

Public

Integrative Analyses of Uterine Transcriptome and MicroRNAome Reveal Compromised LIF-STAT3 Signaling and Progesterone Response in the Endometrium of Patients with Recurrent/Repeated Implantation Failure (RIF)

Published in PLoS ONE • Jun 15, 2016

Authors:

Youngsok Choi

Hye Ryun Kim

Eun Jin Lim

Abstract

Intimate two-way interactions between the implantation-competent blastocyst and receptive uterus are prerequisite for successful embryo implantation. In humans, recurrent/repeated implantation failure (RIF) may occur due to altered uterine receptivity with aberrant gene expression in the endometrium...

Subject

Transcriptome

Biology

Endometrium

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