Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study

A. Regules, Jason; Cicatelli, Susan; W. Bennett, Jason; Paolino, Kristopher; Twomey, Patrick; E. Moon, James; K. Kathcart, April; Hauns, Kevin; Komisar, Jack; N. Qabar, Aziz; A. Davidson, Silas; Dutta, Sheetij; E. Griffith, Matthew; D. Magee, Charles; Wojnarski, Mariusz; Livezey, Jeffrey; T. Kress, Adrian; Waterman, Paige; Jongert, Erik; Wille-Reece, Ulrike; Volkmuth, Wayne; Emerling, Daniel; H. Robinson, William; Lievens, Marc; Morelle, Danielle; Lee, Cynthia; Yassin-Rajkumar, Bebi; Weltzin, Richard; Cohen, Joe; Paris, Robert; C. Waters, Norman; J. Birkett, Ashley; C. Kaslow, David; Ripley Ballou, W.; F. Ockenhouse, Christian; Vekemans, Johan

doi:10.1093/infdis/jiw237

Public

Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study

Published in The Journal of Infectious Diseases • Jun 13, 2016

Authors:

Jason A. Regules

Susan Cicatelli

Jason W. Bennett

Abstract

BACKGROUND: Three full doses of RTS,S/AS01 malaria vaccine provides partial protection against controlled human malaria parasite infection (CHMI) and natural exposure. Immunization regimens, including a delayed fractional third dose, were assessed for potential increased protection against malaria a...

Subject

Malaria vaccine

Malaria

Immunogenicity

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!