Association Between<i>CYP2C19</i>Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack

Wang, Yilong; Zhao, Xingquan; Lin, Jinxi; Li, Hao; Claiborne Johnston, S.; Lin, Yi; Pan, Yuesong; Liu, Liping; Wang, David; Wang, Chunxue; Meng, Xia; Xu, Jianfeng; Wang, Yongjun; the CHANCE investigators, for

doi:10.1001/jama.2016.8662

Public

Association BetweenCYP2C19Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack

Published in JAMA • Jun 27, 2016

Authors:

Yilong Wang

Xingquan Zhao

Jinxi Lin

Abstract

IMPORTANCE: Data are limited regarding the association between CYP2C19 genetic variants and clinical outcomes of patients with minor stroke or transient ischemic attack treated with clopidogrel. OBJECTIVE: To estimate the association between CYP2C19 genetic variants and clinical outcomes of clopidog...

Subject

Medicine

Clopidogrel

Aspirin

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