Rapid Onset of Action of Levodopa in Restless Legs Syndrome: A Double-Blind, Randomized, Multicenter, Crossover Trial

OBJECTIVE: To investigate the efficacy and safety of levodopa plus benserazide in the treatment of restless legs syndrome (RLS), in terms of the frequency of periodic limb movements (PLMs), objective and subjective criteria of sleep, onset of action, and withdrawal effects. DESIGN: A randomized, dou... View More