miR-21-5p renal expression is associated with fibrosis and renal survival in patients with IgA nephropathy

Hennino, Marie-Flore; Buob, David; Van der Hauwaert, Cynthia; Gnemmi, Viviane; Jomaa, Z.; Pottier, Nicolas; Savary, Grégoire; Drumez, Élodie; Noël, Christian; Cauffiez, Christelle; Glowacki, François

doi:10.1038/srep27209

Public

miR-21-5p renal expression is associated with fibrosis and renal survival in patients with IgA nephropathy

Published in Scientific Reports • Jun 6, 2016

Authors:

Marie-Flore Hennino

David Buob

Cynthia Van der Hauwaert

Abstract

IgA nephropathy (IgAN) is the most prevalent primary glomerulonephritis, whose prognosis is highly variable. Interstitial fibrosis is a strong independent prognosis factor. Among microRNA involved in renal fibrogenesis, only few have been investigated in IgAN. In the context of IgAN, we aimed to ana...

Subject

Medicine

Nephropathy

Internal medicine

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