SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism

Lotte Christensen, Lise; True, Kirsten; P. Hamilton, Mark; M. Nielsen, Morten; Djodji Damas, Nkerorema; Kroun Damgaard, Christian; Ongen, Halit; T. Dermitzakis, Emmanouil; B. Bramsen, Jesper; Skou Pedersen, Jakob; H. Lund, Anders; Vang, Søren; Stribolt, Katrine; Rørbæk Madsen, Mogens; Laurberg, Søren; E. McGuire, Sean; F. Ørntoft, Torben; L. Andersen, Claus

doi:10.1016/j.molonc.2016.06.003

Public

SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism

Published in Molecular Oncology • Jun 26, 2016

Authors:

Lise Lotte Christensen

Kirsten True

Mark P. Hamilton

Abstract

It is well established that lncRNAs are aberrantly expressed in cancer where they have been shown to act as oncogenes or tumor suppressors. RNA profiling of 314 colorectal adenomas/adenocarcinomas and 292 adjacent normal colon mucosa samples using RNA-sequencing demonstrated that the snoRNA host gen...

Subject

Wnt signaling pathway

Colorectal cancer

Lipid metabolism

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