Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

Hou, Liping; E. Bergen, Sarah; Akula, Nirmala; Song, Jie; M. Hultman, Christina; Landén, Mikael; Adli, Mazda; Alda, Martin; Ardau, Raffaella; Arias, Bárbara; Aubry, Jean-Michel; Backlund, Lena; A. Badner, Judith; B. Barrett, Thomas; Bauer, Michael; T. Baune, Bernhard; Bellivier, Frank; Benabarre, Antonio; Bengesser, Susanne; H. Berrettini, Wade; Kumar Bhattacharjee, Abesh; M. Biernacka, Joanna; Birner, Armin; S. Bloss, Cinnamon; Brichant‐Petitjean, Clara; T. Bui, Elise; Byerley, William; Cervantes, Pablo; Chillotti, Caterina; Cichon, Sven; Colom, Francesc; Coryell, William; W. Craig, David; Cruceanu, Cristiana; M. Czerski, Piotr; Davis, Tony; Dayer, Alexandre; Degenhardt, Franziska; Del Zompo, Maria; Raymond DePaulo, J.; J. Edenberg, Howard; Étain, Bruno; Falkai, Peter; Foroud, Tatiana; J. Forstner, Andreas; Frisén, Louise; A. Frye, Mark; M. Fullerton, Janice; Gard, Sébastien; Garnham, Julie; S. Gershon, Elliot; S. Goes, Fernando; A. Greenwood, Tiffany; Grigoroiu‐Serbânescu, Maria; Hauser, Joanna; Heilbronner, Urs; Heilmann‐Heimbach, Stefanie; Herms, Stefan; Hipolito, Maria; Hitturlingappa, Shashi; Hoffmann, Per; Hofmann, Andrea; Jamain, Stéphane; Jiménez, Esther; Kahn, Jean‐Pierre; Kassem, Layla; R. Kelsoe, John; Kittel‐Schneider, Sarah; Kliwicki, Sebastian; L. Koller, Daniel; König, Barbara; Lackner, Nina; Laje, Gonzalo; Lang, Maren; Lavebratt, Catharina; Lawson, William; Leboyer, Marion; G. Leckband, Susan; Liu, Chunyu; Maaser, Anna; B. Mahon, Pamela; Maier, Wolfgang; Maj, Mario; Manchia, Mirko; Martinsson, Lina; J. McCarthy, Michael; L. McElroy, Susan; G. McInnis, Melvin; Anne McKinney, R.; B. Mitchell, Philip; Mitjans, Marina; M. Mondimore, Francis; Monteleone, Palmiero; W. Mühleisen, Thomas; M. Nievergelt, Caroline; M. Nöthen, Markus; Novák, Tomáš; I. Nürnberger, John; Nwulia, Evaristus; Ösby, Urban; Pfennig, Andrea; B. Potash, James; Propping, Peter; Reif, Andreas; Z. Reininghaus, Eva; P. Rice, John; Rietschel, Marcella; A. Rouleau, Guy; Rybakowski, Janusz; Schalling, Martin; A. Scheftner, William; R. Schofield, Peter; J. Schork, Nicholas; G. Schulze, Thomas; Schumacher, Johannes; Schweizer, Barbara; Severino, Giovanni; Shekhtman, Tatyana; D. Shilling, Paul; Simhandl, Christian; Slaney, Claire; N. Smith, Erin; Squassina, Alessio; Stamm, Thomas; Stopková, Pavla; Streit, Fabian; Strohmaier, Jana; Szelinger, Szabolcs; K. Tighe, Sarah; Tortorella, Alfonso; Turecki, Gustavo; Vieta, Eduard; Volkert, Julia; H. Witt, Stephanie; Jordan Wright, A.; P. Zandi, Peter; Zhang, Peng; Zöllner, Sebastian; J. McMahon, Francis

doi:10.1093/hmg/ddw181

Public

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

Published in Human Molecular Genetics • Jun 21, 2016

Authors:

Liping Hou

Sarah E. Bergen

Nirmala Akula

Abstract

Bipolar disorder (BD) is a genetically complex mental illness characterized by severe oscillations of mood and behaviour. Genome-wide association studies (GWAS) have identified several risk loci that together account for a small portion of the heritability. To identify additional risk loci, we perfo...

Subject

Genome-wide association study

Bipolar disorder

Genetics

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