<sup>225</sup>Ac-PSMA-617 for PSMA-Targeted α-Radiation Therapy of Metastatic Castration-Resistant Prostate Cancer

Kratochwil, Clemens; Bruchertseifer, Frank; L. Giesel, Frederik; Weis, Mirjam; A. Verburg, Frederik; M. Mottaghy, Felix; Kopka, Klaus; Apostolidis, Christos; Haberkorn, Uwe; Morgenstern, Aliyah

doi:10.2967/jnumed.116.178673

Public

225Ac-PSMA-617 for PSMA-Targeted α-Radiation Therapy of Metastatic Castration-Resistant Prostate Cancer

Published in Journal of Nuclear Medicine • Jul 7, 2016

Authors:

Clemens Kratochwil

Frank Bruchertseifer

Frederik L. Giesel

Abstract

Prostate-specific membrane antigen (PSMA) is a promising target in prostate cancer. Recently, we started the first-in-human treatment with an α-radionuclide–labeled PSMA ligand. Although the case series is still ongoing, we here report in advance about two patients in highly challenging clinical sit...

Subject

Prostate cancer

Medicine

Glutamate carboxypeptidase II

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