Personalized peptide vaccine-induced immune response associated with long-term survival of a metastatic cholangiocarcinoma patient

Löffler, Markus; Anoop Chandran, P.; Laske, Karoline; Schroeder, Christopher; Bonzheim, Irina; Walzer, Mathias; J. Hilke, Franz; Trautwein, Nico; J. Kowalewski, Daniel; Schuster, Heiko; Günder, Marc; A. Carcamo Yañez, Viviana; Mohr, Christopher; Sturm, Marc; Phuc Nguyen, Huu; Rieß, Olaf; Bauer, Peter; Nahnsen, Sven; Nadalin, Silvio; Zieker, Derek; Glatzle, Jörg; Thiel, Karolin; Schneiderhan‐Marra, Nicole; Clasen, Stephan; Bösmüller, Hans; Fend, Falko; Kohlbacher, Oliver; Gouttefangeas, Cécile; Stevanović, Stefan; Königsrainer, Alfred; Rammensee, Hans‐Georg

doi:10.1016/j.jhep.2016.06.027

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Personalized peptide vaccine-induced immune response associated with long-term survival of a metastatic cholangiocarcinoma patient

Published in Journal of Hepatology • Jul 9, 2016

Authors:

Markus Löffler

P. Anoop Chandran

Karoline Laske

Abstract

BACKGROUND & AIMS: We report a novel experimental immunotherapeutic approach in a patient with metastatic intrahepatic cholangiocarcinoma. In the 5year course of the disease, the initial tumor mass, two local recurrences and a lung metastasis were surgically removed. Lacking alternative treatment op...

Subject

Medicine

Peptide vaccine

Immune system

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