In vivo cortical spreading pattern of tau and amyloid in the Alzheimer disease spectrum

Cho, Hanna; Yong Choi, Jae; Song Hwang, Mi; Jin Kim, You; Lee, Hye‐Mi; Sun Lee, Hye; Lee, Jae‐Hoon; Hoon Ryu, Young; Sik Lee, Myung; Hyoung Lyoo, Chul

doi:10.1002/ana.24711

Public

In vivo cortical spreading pattern of tau and amyloid in the Alzheimer disease spectrum

Published in Annals of Neurology • Jun 20, 2016

Authors:

Hanna Cho

Jae Yong Choi

Mi Song Hwang

Abstract

OBJECTIVE: To determine the in vivo cortical spreading pattern of tau and amyloid and to establish positron emission tomography (PET) image-based tau staging in the Alzheimer disease (AD) spectrum. METHODS: We included 195 participants (53 AD, 52 amnestic mild cognitive impairment [MCI], 23 nonamnes...

Subject

Posterior cingulate

Neocortex

Amyloid (mycology)

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