Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

Iturria‐Medina, Yasser; C. Sotero, Roberto; Toussaint, P.-J.; Mateos-Pérez, J.M.; C. Evans, Alan; Alzheimer’s Disease Neuroimaging Initiative, The; W. Weiner, Michael; Aisen, Paul; C. Petersen, Ronald; R. Jack, Clifford; J. Jagust, William; Q. Trojanowki, John; W. Toga, Arthur; Beckett, Laurel; C. Green, Robert; J. Saykin, Andrew; C. Morris, John; M. Shaw, Leslie; S. Khachaturian, Zaven; Sorensen, Greg; Kuller, Lew; Raichle, Marc; M. Paul, Steven; Davies, Peter; Fillit, Howard; Hefti, Franz; Holtzman, Davie; Marcel Mesulam, M.; Z. Potter, William; J. Snyder, Peter; J. Schwartz, Adam; Montine, Tom; G. Thomas, Ronald; Donohue, Michael; Walter, Sarah; Gessert, Devon; Sather, Tamie; Jiminez, Gus; Harvey, Danielle; A. Bernstein, Matt; C. Fox, Nick; M. Thompson, Paul; Schuff, Norbert; Borowski, Bret; Gunter, Jeff; L. Senjem, Matthew; Vemuri, Prashanthi; T. Jones, David; Kantarci, Kejal; Ward, Chad; A. Koeppe, Robert; Foster, Norm; M. Reiman, Eric; Chen, Kewei; Mathis, Chet; Landau, Susan; J. Cairns, Nigel; Householder, Erin; Taylor‐Reinwald, Lisa; Lee, Virginia; Korecka, Magdalena; Figurski, Michal; Crawford, Karen; Neu, Scott; Foroud, Tatiana; Potkin, Steven; Shen, Li; Faber, Kelley; Kim, Sungeun; Nho, Kwangsik; J. Thal, Leon; Buckholtz, Neil; Albert, Marylyn; Frank, Richard; Hsiao, John; Kaye, Jeffrey; F. Quinn, Joseph; Lind, Betty; Carter, Raina; Dolen, Sara; S. Schneider, Lon; Pawluczyk, Sonia; Beccera, Mauricio; Teodoro, Liberty; M. Spann, Bryan; B. Brewer, James; Vanderswag, Helen; Fleisher, Adam; L. Heidebrink, Judith; Lord, Joanne; S. Mason, Sara; S. Albers, Colleen; S. Knopman, David; Johnson, Kris; S. Doody, Rachelle; Villanueva‐Meyer, Javier; Chowdhury, Munir; Rountree, Susan; Dang, Mimi; Stern, Yaakov; S. Honig, Lawrence; L. Bell, Karen; M. Ances, Beau; Carroll, Maria; Leon, Sue; A. Mintun, Mark; Schneider, Stacy; Oliver, Angela; Marson, Daniel; Griffith, Randall; Clark, David; Geldmacher, David; Brockington, John; D. Roberson, Erik; Grossman, Hillel; Mitsis, Effie; de Toledo‐Morrell, Leyla; C. Shah, Raj; Duara, Ranjan; Varón, Daniel; T. Greig, Maria; Roberts, Peggy; Albert, Marilyn; U. Onyike, Chiadi; D’Agostino, Daniel; Kielb, Stephanie; E. Galvin, James; Cerbone, Brittany; A. Michel, Christina; Rusinek, Henry; J. de Leon, Mony; Glodzik, Lidia; De Santi, Susan; Murali Doraiswamy, P.; R. Petrella, Jeffrey; Z. Wong, Terence; E. Arnold, Steven; Karlawish, Jason; A. Wolk, David; D. Smith, Charles; A. Jicha, Gregory; Hardy, Peter; Sinha, Partha; Oates, Elizabeth; Conrad, Gary; L. López, Oscar; Oakley, MaryAnn; M. Simpson, Donna; P. Porsteinsson, Anton; S. Goldstein, Bonnie; Martin, Kim; M. Makino, Kelly; Saleem Ismail, M.; Brand, Connie; A. Mulnard, Ruth; Thai, Gaby; Mc-Adams-Ortiz, Catherine; Womack, Kyle; Mathews, Dana; Quiceno, Mary; Diaz‐Arrastia, Ramon; King, Richard; Weiner, Myron; Martin-Cook, Kristen; D. Devous, Michael; I. Levey, Allan; J. Lah, James; S. Cellar, Janet; M. Burns, Jeffrey; S. Anderson, Heather; H. Swerdlow, Russell; G. Apostolova, Liana; Tingus, Kathleen; Woo, Ellen; Silverman, Daniel; H. Lu, Po; Bartzokis, George; R. Graff‐Radford, Neill; Parfitt, Francine; Kendall, Tracy; Johnson, Heather; R. Farlow, Martin; Hake, AnnMarie; R. Matthews, Brandy; Herring, Scott; Hunt, Cynthia; H. van Dyck, Christopher; E. Carson, Richard; G. MacAvoy, Martha; Chertkow, Howard; Bergman, Howard; Hosein, Chris; E. Black, Sandra; Stefanovic, Bojana; Caldwell, Curtis; Robin Hsiung, Ging‐Yuek; Feldman, Howard; Mudge, Benita; Assaly, Michele; Kertesz, Andrew; Rogers, John; Bernick, Charles; Munic, Donna; Kerwin, Diana; Mesulam, Marek-Marsel; Lipowski, Kristine; Wu, Chuang-Kuo; Johnson, Nancy; Sadowsky, Carl; Martínez, Walter; Villena, Teresa; Scott Turner, Raymond; Johnson, Kathleen; Reynolds, Brigid; A. Sperling, Reisa; A. Johnson, Keith; A. Marshall, Gad; Frey, Meghan; Lane, Barton; Rosen, Allyson; Tinklenberg, Jared; N. Sabbagh, Marwan; M. Belden, Christine; A. Jacobson, Sandra; A. Sirrel, Sherye; W. Kowall, Neil; Killiany, Ronald; E. Budson, Andrew; Norbash, Alexander; Lynn Johnson, Patricia; Allard, Joanne; J. Lerner, Alan; Ogrocki, Paula; Hudson, Leon; Fletcher, Evan; Carmichael, Owen; Olichney, John; DeCarli, Charles; Kittur, Smita; Borrie, Michael; Lee, T-Y; Bartha, Robert; C. Johnson, Sterling; Asthana, Sanjay; M. Carlsson, Cynthia; G. Potkin, Steven; Preda, Adrian; Nguyen, Dana; N. Tariot, Pierre; Reeder, Stephanie; Bates, Vernice; Capote, Horacio; Rainka, Michelle; W. Scharre, Douglas; Kataki, Maria; Adeli, Anahita; A. Zimmerman, Earl; Celmins, Dzintra; D. Brown, Alice; D. Pearlson, Godfrey; Blank, Karen; Anderson, Karen; B. Santulli, Robert; J. Kitzmiller, Tamar; S. Schwartz, Eben; M. Sink, Kaycee; D. Williamson, Jeff; Garg, Pradeep; Watkins, Franklin; R. Ott, Brian; Querfurth, Henry; Tremont, Geoffrey; Salloway, Stephen; Malloy, Paul; Correia, Stephen; J. Rosen, Howard; L. Miller, Bruce; Mintzer, Jacobo; Spicer, Kenneth; Bachman, David; Finger, Elizabeth; Pasternak, Stephen; Rachinsky, Irina; Drost, Dick; Pomara, Nunzio; Hernando, Raymundo; Sarrael, Antero; K. Schultz, Susan; L. Boles Ponto, Laura; Shim, Hyungsub; E. Smith, Karen; Relkin, Norman; Chaing, Gloria; Raudin, Lisa; Smith, Amanda; Fargher, Kristin; Ashok Raj, Balebail; C. Neylan, Thomas; Grafman, Jordan; Davis, Melissa; Morrison, Rosemary; Hayes, Jacqueline; Finley, Shannon; E. Friedl, Karl; Fleischman, Debra; Arfanakis, Konstantinos; James, Olga; Massoglia, Dino; Jay Fruehling, J.; Harding, Sandra; R. Peskind, Elaine; C. Petrie, Eric; Li, Gail; A. Yesavage, Jerome; L. Taylor, Joy; J. Furst, Ansgar

doi:10.1038/ncomms11934

Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis | NobleBlocks