Antiretroviral Therapy for the Prevention of HIV-1 Transmission

S. Cohen, Myron; Qing Chen, Ying; McCauley, Marybeth; Gamble, Theresa; C. Hosseinipour, Mina; Kumarasamy, Nagalingeswaran; Hakim, James; Kumwenda, Johnstone; Grinsztejn, Beatriz; Henrique Pilotto, José; Godbole, Sheela; Chariyalertsak, Suwat; Santos, Breno; H. Mayer, Kenneth; Hoffman, Irving; H. Eshleman, Susan; Piwowar‐Manning, Estelle; Cottle, Leslie; C. Zhang, Xinyi; Makhema, Joseph; Mills, Lisa; Panchia, Ravindre; Faesen, Sharlaa; J. Eron, Joseph; E. Gallant, Joel; V. Havlir, Diane; Swindells, Susan; Elharrar, Vanessa; Burns, David; E. Taha, Taha; Nielsen‐Saines, Karin; D. Celentano, David; Essex, Max; E. Hudelson, Sarah; D. Redd, Andrew; R. Fleming, Thomas

doi:10.1056/nejmoa1600693

Public

Antiretroviral Therapy for the Prevention of HIV-1 Transmission

Published in New England Journal of Medicine • Jul 18, 2016

Authors:

Myron S. Cohen

Ying Qing Chen

Marybeth McCauley

Abstract

BACKGROUND: An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052 trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked infections caused by human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. ART was then offered to a...

Subject

Serodiscordant

Antiretroviral therapy

Human immunodeficiency virus (HIV)

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