miR-423-5p contributes to a malignant phenotype and temozolomide chemoresistance in glioblastomas.

S, Li; A, Zeng; Q, Hu; W, Yan; Y, Liu; Y, You

doi:10.1093/neuonc/now129

Public

miR-423-5p contributes to a malignant phenotype and temozolomide chemoresistance in glioblastomas.

Shared by NobleBlocks on Jul 28, 2016 • 12:00 AM UTC

Authors:

Li S

Zeng A

Hu Q

Abstract

Background Gliomas are based on a genetic abnormality and present with a dismal prognosis. MicroRNAs (miRNAs) are considered to be important mediators of gene expression in glioma tissues.Methods Real-time PCR was used to analyze the expression of microRNA-423-5p (miR-423-5p) in human glioma samples...

Subject

Glioma

Chemoresistance

Mir-423-5p

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