Comprehensive Analysis of the Transcriptional and Mutational Landscape of Follicular and Papillary Thyroid Cancers

Yoo, Seong‐Keun; Lee, Seungbok; Kim, Su‐jin; Jee, Hyeon‐Gun; Kim, Byoung-Ae; Cho, Hyesun; Shin Song, Young; Wook Cho, Sun; Won, Jae‐Kyung; Shin, Jong-Yeon; Joon Park, Do; Kim, Jong‐Il; Eun Lee, Kyu; Joo Park, Young; Seo, Jeong‐Sun

doi:10.1371/journal.pgen.1006239

Public

Comprehensive Analysis of the Transcriptional and Mutational Landscape of Follicular and Papillary Thyroid Cancers

Published in PLoS Genetics • Aug 5, 2016

Authors:

Seong‐Keun Yoo

Seungbok Lee

Su‐jin Kim

Abstract

Follicular thyroid carcinoma (FTC) and benign follicular adenoma (FA) are indistinguishable by preoperative diagnosis due to their similar histological features. Here we report the first RNA sequencing study of these tumors, with data for 30 minimally invasive FTCs (miFTCs) and 25 FAs. We also compa...

Subject

PAX8

Neuroblastoma RAS viral oncogene homolog

PTEN

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