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Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium.

Published in Biological psychiatry • Feb 15, 2017
Authors:
Robert A Power
,
Katherine E Tansey
,
Henriette Nørmølle Buttenschøn

Abstract

BACKGROUND: Major depressive disorder (MDD) is a disabling mood disorder, and despite a known heritable component, a large meta-analysis of genome-wide association studies revealed no replicable genetic risk variants. Given prior evidence of heterogeneity by age at onset in MDD, we tested whether ge...

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