Effect of Radiosurgery Alone vs Radiosurgery With Whole Brain Radiation Therapy on Cognitive Function in Patients With 1 to 3 Brain Metastases

D. Brown, Paul; A. Jaeckle, Kurt; V. Ballman, Karla; Farace, Elana; H. Cerhan, Jane; Keith Anderson, S.; W. Carrero, Xiomara; G. Barker, Fred; L. Deming, Richard; H. Burri, Stuart; Ménard, Cynthia; Chung, Caroline; W. Stieber, Volker; E. Pollock, Bruce; Galanis, Evanthia; C. Buckner, Jan; L. Asher, Anthony

doi:10.1001/jama.2016.9839

Public

Effect of Radiosurgery Alone vs Radiosurgery With Whole Brain Radiation Therapy on Cognitive Function in Patients With 1 to 3 Brain Metastases

Published in JAMA • Jul 26, 2016

Authors:

Paul D. Brown

Kurt A. Jaeckle

Karla V. Ballman

Abstract

IMPORTANCE: Whole brain radiotherapy (WBRT) significantly improves tumor control in the brain after stereotactic radiosurgery (SRS), yet because of its association with cognitive decline, its role in the treatment of patients with brain metastases remains controversial. OBJECTIVE: To determine wheth...

Subject

Medicine

Radiosurgery

Quality of life (healthcare)

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