Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis

Banushi, Blerida; Forneris, Federico; Straatman-Iwanowska, Anna; Strange, Adam; Lyne, Anne-Marie; Rogerson, Clare; J. Burden, Jemima; Heywood, Wendy; Hanley, Joanna; Doykov, Ivan; R. Straatman, Kees; Smith, Holly; Bem, Danai; Kriston-Vizi, János; Ariceta, Gema; Risteli, Maija; Wang, Chunguang; Ardill, R; Zaniew, Marcin; Latka-Grot, Julita; N. Waddington, Simon; J. Howe, Stewen; Ferraro, Francesco; Gjinovci, Asllan; P. Lawrence, Scott; Marsh, Mark; Girolami, Mark; Bozec, Laurent; Mills, Kevin; Gissen, Paul

doi:10.1038/ncomms12111

Public

Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis

Published in Nature Communications • Jul 20, 2016

Authors:

Blerida Banushi

Federico Forneris

Anna Straatman-Iwanowska

Abstract

Post-translational modifications are necessary for collagen precursor molecules (procollagens) to acquire final shape and function. However, the mechanism and contribution of collagen modifications that occur outside the endoplasmic reticulum and Golgi are not understood. We discovered that VIPAR, w...

Subject

Golgi apparatus

Endoplasmic reticulum

Cell biology

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