Downregulation of the long noncoding RNA GAS5-AS1 contributes to tumor metastasis in non-small cell lung cancer

Wu, Ying; Lyu, Hui; Liu, Hongbing; Shi, Xuefei; Song, Yong; Liu, Bolin

doi:10.1038/srep31093

Public

Downregulation of the long noncoding RNA GAS5-AS1 contributes to tumor metastasis in non-small cell lung cancer

Published in Scientific Reports • Aug 4, 2016

Authors:

Ying Wu

Hui Lyu

Hongbing Liu

Abstract

Long noncoding RNA (lncRNA) plays pivotal roles in cancer development. To date, only a small number of lncRNAs have been characterized at functional level. Here, we discovered a novel lncRNA termed GAS5-AS1 as a tumor suppressor in non-small cell lung cancer (NSCLC). The expression of GAS5-AS1 in NS...

Subject

GAS5

Cancer research

Downregulation and upregulation

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