Increased global placental DNA methylation levels are associated with gestational diabetes

Reichetzeder, Christoph; Emantoko Dwi Putra, Sulistyo; Pfab, Thiemo; Slowinski, Torsten; Neuber, Corinna; Kleuser, Burkhard; Hocher, Berthold

doi:10.1186/s13148-016-0247-9

Public

Increased global placental DNA methylation levels are associated with gestational diabetes

Published in Clinical Epigenetics • Jul 25, 2016

Authors:

Christoph Reichetzeder

Sulistyo Emantoko Dwi Putra

Thiemo Pfab

Abstract

BACKGROUND: Gestational diabetes mellitus (GDM) is associated with adverse pregnancy outcomes. It is known that GDM is associated with an altered placental function and changes in placental gene regulation. More recent studies demonstrated an involvement of epigenetic mechanisms. So far, the focus r...

Subject

DNA methylation

Gestational diabetes

Epigenetics

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