Two Phase 3 Trials of Adalimumab for Hidradenitis Suppurativa

B. Kimball, Alexa; M. Okun, Martin; Williams, David; B. Gottlieb, Alice; Papp, Kim; C. Zouboulis, Christos; W. Armstrong, April; A. Kerdel, Francisco; H. Gold, Michael; Forman, Seth; J. Korman, Neil; J. Giamarellos‐Bourboulis, Evangelos; Crowley, Jeffrey; Lynde, Charles; Reguiaï, Z.; Prens, Errol-Prospero; Alwawi, Eihab; M. Mostafa, Nael; Pinsky, Brett; Sundaram, Murali; Gu, Yihua; M. Carlson, Dawn; B. E. Jemec, Gregor

doi:10.1056/nejmoa1504370

Public

Two Phase 3 Trials of Adalimumab for Hidradenitis Suppurativa

Published in New England Journal of Medicine • Aug 3, 2016

Authors:

Alexa B. Kimball

Martin M. Okun

David Williams

Abstract

BACKGROUND: Hidradenitis suppurativa is a painful, chronic inflammatory skin disease with few options for effective treatment. In a phase 2 trial, adalimumab, an antibody against tumor necrosis factor α, showed efficacy against hidradenitis suppurativa. METHODS: PIONEER I and II were similarly desig...

Subject

Hidradenitis suppurativa

Adalimumab

Medicine

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