Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

Postmus, Iris; R. Warren, Helen; Trompet, Stella; J. Arsenault, Benoît; L. Avery, Christy; C Bis, Joshua; I. Chasman, Daniel; E. de Keyser, Catherine; Deshmukh, Harshal; S. Evans, Daniel; Feng, QiPing; Li, Xiaohui; A. J. Smit, Roelof; V. Smith, Albert; Sun, Fangui; D. Taylor, Kent; M. Arnold, Alice; R. Barnes, Michael; J. Barratt, Bryan; Betteridge, John; Matthijs Boekholdt, S.; Boerwinkle, Eric; M. Buckley, Brendan; Ida Chen, Y-D; J. M. de Craen, Anton; R. Cummings, Steven; C. Denny, Joshua; Dubé, Marie‐Pierre; N. Durrington, Paul; Eiríksdóttir, Guðný; Ford, Ian; Guo, Xiuqing; B. Harris, Tamara; R. Heckbert, Susan; Hofman, Albert; Kees Hovingh, G.; J.P. Kastelein, John; J. Launer, Leonore; Liu, Ching‐Ti; Liu, Ching‐Ti; Lumley, Thomas; McKeigue, Paul; B. Munroe, Patricia; Neil, Andrew; A. Nickerson, Deborah; Nyberg, Fredrik; OʼBrien, Eoin; J. O’Donnell, Christopher; S. Post, Wendy; R Poulter, Neil; S. Vasan, Ramachandran; Rice, Kenneth; S. Rich, Stephen; Rivadeneira, Fernando; Sattar, Naveed; Sever, Peter; Shaw‐Hawkins, Sue; C. Shields, Denis; Eline Slagboom, P.; L. Smith, Nicholas; D. Smith, Joshua; Sotoodehnia, Nona; Stanton, Alice; J. Stott, David; H. Stricker, Bruno; Stürmer‎, Til; G. Uitterlinden, André; Wei, Wei‐Qi; G. J. Westendorp, Rudi; A. Whitsel, Eric; L. Wiggins, Kerri; A. Wilke, Russell; M. Ballantyne, Christie; M. Colhoun, Helen; Adrienne Cupples, L.; H. Franco, Oscar; Guðnason, Vilmundur; A. Hitman, G.; N A Palmer, Colin; M. Psaty, Bruce; M. Ridker, Paul; M. Stafford, Jeanette; Stein, Charles; Tardif, Jean‐Claude; J. Caulfield, Mark; Wouter Jukema, J.; I. Rotter, Jerome; M. Krauss, Ronald

doi:10.1136/jmedgenet-2016-103966

Public

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

Published in Journal of Medical Genetics • Sep 1, 2016

Authors:

Iris Postmus

Helen R. Warren

Stella Trompet

Abstract

Background In addition to lowering low density lipoprotein cholesterol (LDL-C), statin therapy also raises high density lipoprotein cholesterol (HDL-C) levels. Inter-individual variation in HDL-C response to statins may be partially explained by genetic variation. Methods and results We performed a ...

Subject

Cholesterol

Genome-wide association study

Association (psychology)

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