Detection of Circulating Mucorales DNA in Critically Ill Burn Patients: Preliminary Report of a Screening Strategy for Early Diagnosis and Treatment

Legrand, Matthieu; Gits‐Muselli, Maud; Boutin, Louis; Garcia‐Hermoso, Dea; Maurel, Véronique; Soussi, Sabri; Benyamina, Mourad; Ferry, Axelle; Chaussard, Maïté; Hamane, Samia; Denis, Blandine; Touratier, Sophie; Guigue, Nicolas; Fréalle, Émilie; Jeanne, Mathieu; Shaal, Jean-Vivien; Soler, C.; Mimoun, Maurice; Chaouat, Marc; Lafaurie, Matthieu; Mebazaa, Alexandre; Bretagne, Stéphane; Alanio, Alexandre

doi:10.1093/cid/ciw563

Public

Detection of Circulating Mucorales DNA in Critically Ill Burn Patients: Preliminary Report of a Screening Strategy for Early Diagnosis and Treatment

Published in Clinical Infectious Diseases • Aug 17, 2016

Authors:

Matthieu Legrand

Maud Gits‐Muselli

Louis Boutin

Abstract

BACKGROUND: Invasive wound mucormycosis (IWM) is associated with an extremely poor outcome among critically ill burn patients. We describe the detection of circulating Mucorales DNA (cmDNA) for the early diagnosis of IWM in those patients and report the potential value of detecting cmDNA for treatme...

Subject

Medicine

Clinical endpoint

Critically ill

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