Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis

Currie, Gemma; Taylor, Alison; Fujita, Toshiro; Ohtsu, Hiroshi; Lindhardt, Morten; Rossing, Peter; Boesby, Lene; C. Edwards, Nicola; J. Ferro, Charles; Townend, John; H. van den Meiracker, Anton; G. Saklayen, Mohammad; Oveisi, Sonia; G. Jardine, Alan; Delles, Christian; Preiss, David; B. Mark, Patrick

doi:10.1186/s12882-016-0337-0

Public

Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis

Published in BMC Nephrology • Sep 7, 2016

Authors:

Gemma Currie

Alison Taylor

Toshiro Fujita

Abstract

BACKGROUND: Hypertension and proteinuria are critically involved in the progression of chronic kidney disease. Despite treatment with renin angiotensin system inhibition, kidney function declines in many patients. Aldosterone excess is a risk factor for progression of kidney disease. Hyperkalaemia i...

Subject

Medicine

Proteinuria

Mineralocorticoid receptor

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