Propionate Ameliorates Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Reducing Inflammation and Oxidative Stress

Tong, Ling‐Chang; Wang, Yue; Wang, Zhi-bin; Liu, Wei‐Ye; Sun, Sheng; Li, Ling; Su, Ding‐Feng; Zhang, Lichao

doi:10.3389/fphar.2016.00253

Public

Propionate Ameliorates Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Reducing Inflammation and Oxidative Stress

Published in Frontiers in Pharmacology • Aug 14, 2016

Authors:

Ling‐Chang Tong

Yue Wang

Zhi-bin Wang

Abstract

Propionate is a short chain fatty acid that is abundant as butyrate in the gut and blood. However, propionate has not been studied as extensively as butyrate in the treatment of colitis. The present study was to investigate the effects of sodium propionate on intestinal barrier function, inflammatio...

Subject

Colitis

Propionate

Oxidative stress

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