Clinical Effects of Driver Somatic Mutations on the Outcomes of Patients With Myelodysplastic Syndromes Treated With Allogeneic Hematopoietic Stem-Cell Transplantation

Giovanni Della Porta, Matteo; Gallì, Anna; Bacigalupo, Andrea; Zibellini, Silvia; Bernardi, Massimo; Rizzo, Ettore; Allione, Bernardino; Teresa Van Lint, Maria; Pioltelli, Pietro; Marenco, Paola; Bosi, Alberto; Teresa Voso, Maria; Sica, Simona; Cuzzola, Mariella; Angelucci, Emanuele; Rossi, Marianna; Ubezio, Marta; Malovini, Alberto; Limongelli, Ivan; Valeria Ferretti, Virginia; Spinelli, Orietta; Tresoldi, Cristina; Pozzi, Sarah; Luchetti, Silvia; Anna Pezzetti, Laura; Catricalà, Silvia; Milanesi, Chiara; Riva, Alberto; Bruno, Benedetto; Ciceri, Fabio; Bonifazi, Francesca; Bellazzi, Riccardo; Papaemmanuil, Elli; Santoro, Armando; Paolo Alessandrino, Emilio; Rambaldi, Alessandro; Cazzola, Mario

doi:10.1200/jco.2016.67.3616

Public

Clinical Effects of Driver Somatic Mutations on the Outcomes of Patients With Myelodysplastic Syndromes Treated With Allogeneic Hematopoietic Stem-Cell Transplantation

Published in Journal of Clinical Oncology • Sep 7, 2016

Authors:

Matteo Giovanni Della Porta

Anna Gallì

Andrea Bacigalupo

Abstract

PURPOSE: The genetic basis of myelodysplastic syndromes (MDS) is heterogeneous, and various combinations of somatic mutations are associated with different clinical phenotypes and outcomes. Whether the genetic basis of MDS influences the outcome of allogeneic hematopoietic stem-cell transplantation ...

Subject

Myelodysplastic syndromes

Medicine

International Prognostic Scoring System

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