The prominent role of serotonergic degeneration in apathy, anxiety and depression in<i>de novo</i>Parkinson’s disease

Maillet, Audrey; Krack, Paul; Lhommée, Eugénie; Météreau, Élise; Klinger, Hélène; Favre, Émilie; Le Bars, Didier; Schmitt, Emmanuelle; Bichon, Amélie; Pélissier, Pierre; Fraix, Valérie; Castrioto, Anna; Sgambato, Véronique; Broussolle, Emmanuel; Tremblay, Léon; Thobois, Stéphane

doi:10.1093/brain/aww162

Public

The prominent role of serotonergic degeneration in apathy, anxiety and depression inde novoParkinson’s disease

Published in Brain • Aug 17, 2016

Authors:

Audrey Maillet

Paul Krack

Eugénie Lhommée

Abstract

SEE SCHRAG AND POLITIS DOI101093/AWW190 FOR A SCIENTIFIC COMMENTARY ON THIS ARTICLE: Apathy, which can occur separately or in combination with depression and anxiety, is one of the most frequently encountered neuropsychiatric symptoms in Parkinson's disease. Pathophysiological evidence suggests that...

Subject

Apathy

Putamen

Psychology

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