Varespladib (LY315920) Appears to Be a Potent, Broad-Spectrum, Inhibitor of Snake Venom Phospholipase A2 and a Possible Pre-Referral Treatment for Envenomation

R. Lewin, Matthew; P. Samuel, Stephen; Merkel, Janie; E. Bickler, Philip

doi:10.3390/toxins8090248

Public

Varespladib (LY315920) Appears to Be a Potent, Broad-Spectrum, Inhibitor of Snake Venom Phospholipase A2 and a Possible Pre-Referral Treatment for Envenomation

Published in Toxins • Aug 25, 2016

Authors:

Matthew R. Lewin

Stephen P. Samuel

Janie Merkel

Abstract

Snakebite remains a neglected medical problem of the developing world with up to 125,000 deaths each year despite more than a century of calls to improve snakebite prevention and care. An estimated 75% of fatalities from snakebite occur outside the hospital setting. Because phospholipase A2 (PLA2) a...

Subject

Venom

Snake venom

Envenomation

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