Artemisinin Resistance–Associated K13 Polymorphisms of Plasmodium falciparum in Southern Rwanda, 2010–2015

Tacoli, Costanza; P. Gai, Prabhanjan; Bayingana, Claude; C. Sifft, Kevin; Geus, Dominik; Ndoli, Jules; Sendegeya, Augustin; Bosco Gahutu, Jean; P. Mockenhaupt, Frank

doi:10.4269/ajtmh.16-0483

Public

Artemisinin Resistance–Associated K13 Polymorphisms of Plasmodium falciparum in Southern Rwanda, 2010–2015

Published in American Journal of Tropical Medicine and Hygiene • Aug 30, 2016

Authors:

Costanza Tacoli

Prabhanjan P. Gai

Claude Bayingana

Abstract

Emerging artemisinin resistance is a threat to global malaria control. Mutations in the Plasmodium falciparum Kelch 13 (K13) propeller domain confer artemisinin resistance and constitute molecular markers for its detection and monitoring. We sequenced 222 P. falciparum isolates obtained from communi...

Subject

Artemisinin

Plasmodium falciparum

Malaria

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