Effects of Alteplase for Acute Stroke on the Distribution of Functional Outcomes: A Pooled Analysis of 9 Trials.

R Lees, Kennedy; Emberson, Jonathan; Blackwell, Lisa; Bluhmki, Erich; M Davis, Stephen; A Donnan, Geoffrey; C Grotta, James; Kaste, Markku; von Kummer, Rüdiger; G Lansberg, Maarten; I Lindley, Richard; Lyden, Patrick; D Murray, Gordon; A G Sandercock, Peter; Toni, Danilo; Toyoda, Kazunori; M Wardlaw, Joanna; N Whiteley, William; Baigent, Colin; Hacke, Werner; Howard, George; Thrombolysis Trialists’ Collaborators Group, Stroke

doi:10.1161/strokeaha.116.013644

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Effects of Alteplase for Acute Stroke on the Distribution of Functional Outcomes: A Pooled Analysis of 9 Trials.

Shared by NobleBlocks on Sep 1, 2016 • 12:00 AM UTC

Authors:

Kennedy R Lees

Jonathan Emberson

Lisa Blackwell

Abstract

BACKGROUND: Thrombolytic therapy with intravenous alteplase within 4.5 hours of ischemic stroke onset increases the overall likelihood of an excellent outcome (no, or nondisabling, symptoms). Any improvement in functional outcome distribution has value, and herein we provide an assessment of the eff...

Subject

United States

confidence interval

odds ratio

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