70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer

Cardoso, Fátima; J. van’t Veer, Laura; Bogaerts, Jan; Slaets, Leen; Viale, Giuseppe; Delaloge, Suzette; Pierga, Jean‐Yves; Brain, Étienne; Causeret, Sylvain; Delorenzi, Mauro; M. Glas, Annuska; Golfinopoulos, Vassilis; Goulioti, Theodora; Knox, Susan; Matos, Erika; Meulemans, Bart; A. Neijenhuis, Peter; Nitz, Ulrike; Passalacqua, Rodolfo; M. Ravdin, Peter; T. Rubio, Isabel; Saghatchian, Mahasti; J. Smilde, Tineke; Sotiriou, Christos; Stork, Lisette; Straehle, Carolyn; Thomas, Geraldine; M. Thompson, Alastair; M. van der Hoeven, Jacobus; Vuylsteke, Peter; Bernards, René; Tryfonidis, Konstantinos; J. Rutgers, Emiel; Piccart, Martine

doi:10.1056/nejmoa1602253

Public

70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer

Published in New England Journal of Medicine • Aug 24, 2016

Authors:

Fátima Cardoso

Laura J. van’t Veer

Jan Bogaerts

Abstract

BACKGROUND: The 70-gene signature test (MammaPrint) has been shown to improve prediction of clinical outcome in women with early-stage breast cancer. We sought to provide prospective evidence of the clinical utility of the addition of the 70-gene signature to standard clinical-pathological criteria ...

Subject

Breast cancer

Stage (stratigraphy)

Oncology

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