Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species

Guilliams, Martin; Dutertre, Charles‐Antoine; L. Scott, Charlotte; McGovern, Naomi; Sichien, Dorine; Chakarov, Svetoslav; Van Gassen, Sofie; Chen, Jinmiao; Poidinger, Michael; De Prijck, Sofie; J. Tavernier, Simon; Low, Ivy; Erdal Irac, Sergio; Nurfarah Zaini Mattar, Citra; Sumatoh, Hermi; Low, Gillian; John Kit Chung, Tam; Kok Hong Chan, Dedrick; Tan, Ker‐Kan; Lim Kiat Hon, Tony; Fossum, Even; Bogen, Bjarne; Choolani, Mahesh; Kok Yen Chan, Jerry; Larbi, Anis; Luche, Hervé; Henri, Sandrine; Saeys, Yvan; W. Newell, Evan; N. Lambrecht, Bart; MALISSEN, Bernard; Ginhoux, Florent

doi:10.1016/j.immuni.2016.08.015

Public

Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species

Published in Immunity • Sep 1, 2016

Authors:

Martin Guilliams

Charles‐Antoine Dutertre

Charlotte L. Scott

Abstract

Dendritic cells (DCs) are professional antigen-presenting cells that hold great therapeutic potential. Multiple DC subsets have been described, and it remains challenging to align them across tissues and species to analyze their function in the absence of macrophage contamination. Here, we provide a...

Subject

Biology

Flow cytometry

Mass cytometry

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