Genomic prediction of coronary heart disease

Abraham, Gad; S. Havulinna, Aki; G. Bhalala, Oneil; Byars, Sean; De Livera, Alysha; Yetukuri, Laxman; Tikkanen, Emmi; Perola, Markus; Schunkert, Heribert; J.G. Sijbrands, Eric; Palotie, Aarno; J. Samani, Nilesh; Salomaa, Veikko; Ripatti, Samuli; Inouye, Michael

doi:10.1093/eurheartj/ehw450

Public

Genomic prediction of coronary heart disease

Published in European Heart Journal • Sep 21, 2016

Authors:

Gad Abraham

Aki S. Havulinna

Oneil G. Bhalala

Abstract

AIMS: Genetics plays an important role in coronary heart disease (CHD) but the clinical utility of genomic risk scores (GRSs) relative to clinical risk scores, such as the Framingham Risk Score (FRS), is unclear. Our aim was to construct and externally validate a CHD GRS, in terms of lifetime CHD ri...

Subject

Medicine

Framingham Risk Score

Framingham Heart Study

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