Mini Review: Anticholinergic Activity as a Behavioral Pathology of Lewy Body Disease and Proposal of the Concept of “Anticholinergic Spectrum Disorders”

Hori, Koji; Konishi, Kimiko; Hosoi, Misa; Tomioka, Hiroi; Tani, Masayuki; Kitajima, Yuka; Hachisu, Mitsugu

doi:10.1155/2016/5380202

Public

Mini Review: Anticholinergic Activity as a Behavioral Pathology of Lewy Body Disease and Proposal of the Concept of “Anticholinergic Spectrum Disorders”

Published in Parkinson s Disease • Jan 1, 2016

Authors:

Koji Hori

Kimiko Konishi

Misa Hosoi

Abstract

Given the relationship between anticholinergic activity (AA) and Alzheimer's disease (AD), we rereview our hypothesis of the endogenous appearance of AA in AD. Briefly, because acetylcholine (ACh) regulates not only cognitive function but also the inflammatory system, when ACh downregulation reaches...

Subject

Anticholinergic

Lewy body

Medicine

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