LncRNA HOXA11-AS Promotes Proliferation and Invasion of Gastric Cancer by Scaffolding the Chromatin Modification Factors PRC2, LSD1, and DNMT1

Sun, Ming; Nie, Fengqi; Wang, Yunfei; Zhang, Zhihong; Hou, Jiakai; He, Dandan; Xie, Min; Xu, Lin; De, Wei; Wang, Zhaoxia; Wang, Jun

doi:10.1158/0008-5472.can-16-0356

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LncRNA HOXA11-AS Promotes Proliferation and Invasion of Gastric Cancer by Scaffolding the Chromatin Modification Factors PRC2, LSD1, and DNMT1

Published in Cancer Research • Sep 20, 2016

Authors:

Ming Sun

Fengqi Nie

Yunfei Wang

Abstract

Long noncoding RNAs (lncRNA) have been implicated in human cancer but their mechanisms of action are mainly undocumented. In this study, we investigated lncRNA alterations that contribute to gastric cancer through an analysis of The Cancer Genome Atlas RNA sequencing data and other publicly availabl...

Subject

Cancer

Cancer research

Biology

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