Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes

Segerstolpe, Åsa; Palasantza, Athanasia; Eliasson, Pernilla; Andersson, Eva-Marie; Andréasson, Anne‐Christine; Sun, Xiaoyan; Picelli, Simone; Sabirsh, Alan; Clausen, Maryam; Bjursell, Magnus; M. Smith, David; Kasper, Maria; Ämmälä, Carina; Sandberg, Rickard

doi:10.1016/j.cmet.2016.08.020

Public

Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes

Published in Cell Metabolism • Sep 22, 2016

Authors:

Åsa Segerstolpe

Athanasia Palasantza

Pernilla Eliasson

Abstract

Hormone-secreting cells within pancreatic islets of Langerhans play important roles in metabolic homeostasis and disease. However, their transcriptional characterization is still incomplete. Here, we sequenced the transcriptomes of thousands of human islet cells from healthy and type 2 diabetic dono...

Subject

Transcriptome

Biology

Islet

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