Genetic characterization of mcr-1-bearing plasmids to depict molecular mechanisms underlying dissemination of the colistin resistance determinant.

R, Li; M, Xie; J, Zhang; Z, Yang; L, Liu; X, Liu; Z, Zheng; EW, Chan; S, Chen

doi:10.1093/jac/dkw411

Public

Genetic characterization of mcr-1-bearing plasmids to depict molecular mechanisms underlying dissemination of the colistin resistance determinant.

Shared by NobleBlocks on Sep 28, 2016 • 12:00 AM UTC

Authors:

Li R

Xie M

Zhang J

Abstract

Objectives To analyse and compare mcr-1-bearing plasmids from animal Escherichia coli isolates, and to investigate potential mechanisms underlying dissemination of mcr-1.Methods Ninety-seven ESBL-producing E. coli strains isolated from pig farms in China were screened for the mcr-1 gene. Fifteen mcr...

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