Medial reward and lateral non-reward orbitofrontal cortex circuits change in opposite directions in depression

Cheng, Wei; T. Rolls, Edmund; Qiu, Jiang; Liu, Wei; Tang, Yanqing; Huang, Chu‐Chung; Wang, Xinfa; Zhang, Jie; Lin, Wei; Zheng, Lirong; Pu, Juncai; Tsai, Shih‐Jen; C. Yang, Albert; Lin, Ching‐Po; Wang, Fei; Xie, Peng; Feng, Jianfeng

doi:10.1093/brain/aww255

Public

Medial reward and lateral non-reward orbitofrontal cortex circuits change in opposite directions in depression

Published in Brain • Oct 14, 2016

Authors:

Wei Cheng

Edmund T. Rolls

Jiang Qiu

Abstract

The first brain-wide voxel-level resting state functional connectivity neuroimaging analysis of depression is reported, with 421 patients with major depressive disorder and 488 control subjects. Resting state functional connectivity between different voxels reflects correlations of activity between ...

Subject

Orbitofrontal cortex

Precuneus

Neuroscience

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