Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling

Pidsley, Ruth; Zotenko, Elena; J. Peters, Timothy; G. Lawrence, Mitchell; P. Risbridger, Gail; L. Molloy, Peter; Van Djik, Susan; S. Mühlhäusler, Beverly; Stirzaker, Clare; J. Clark, Susan

doi:10.1186/s13059-016-1066-1

Public

Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling

Published in Genome biology • Oct 7, 2016

Authors:

Ruth Pidsley

Elena Zotenko

Timothy J. Peters

Abstract

BACKGROUND: In recent years the Illumina HumanMethylation450 (HM450) BeadChip has provided a user-friendly platform to profile DNA methylation in human samples. However, HM450 lacked coverage of distal regulatory elements. Illumina have now released the MethylationEPIC (EPIC) BeadChip, with new cont...

Subject

Biology

DNA methylation

Genome

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