Regulatory T cells, especially ICOS+ FOXP3+ regulatory T cells, are increased in the hepatocellular carcinoma microenvironment and predict reduced survival

Tu, Jianfei; Ding, Yahui; Ying, Xihui; Wu, Fazong; Zhou, Xin-mu; Zhang, Deng-Ke; Zou, Hai; Ji, Jiansong

doi:10.1038/srep35056

Public

Regulatory T cells, especially ICOS+ FOXP3+ regulatory T cells, are increased in the hepatocellular carcinoma microenvironment and predict reduced survival

Published in Scientific Reports • Oct 11, 2016

Authors:

Jianfei Tu

Yahui Ding

Xihui Ying

Abstract

Abstract Hepatocellular carcinoma (HCC) is a common malignant tumour, especially in Asia. Its prognosis is poor, and there are limited methods for predicting patient survival. This study was carried out to analyse the prognostic value of tumour-infiltrating lymphocytes (TILs), especially regulatory ...

Subject

FOXP3

Hepatocellular carcinoma

CD68

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