Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery

S. Myles, Paul; A. Smith, Julian; Forbes, Andrew; Silbert, Brendan; Jayarajah, Mohandas; Painter, Thomas; James Cooper, D.; Marasco, Silvana; J. McNeil, John; S. Bussières, Jean; McGuinness, Shay; Byrne, Kelly; T.V. Chan, Matthew; Landoni, Giovanni; Wallace, Sophie

doi:10.1056/nejmoa1606424

Public

Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery

Published in New England Journal of Medicine • Oct 23, 2016

Authors:

Paul S. Myles

Julian A. Smith

Andrew Forbes

Abstract

BACKGROUND: Tranexamic acid reduces the risk of bleeding among patients undergoing cardiac surgery, but it is unclear whether this leads to improved outcomes. Furthermore, there are concerns that tranexamic acid may have prothrombotic and proconvulsant effects. METHODS: In a trial with a 2-by-2 fact...

Subject

Tranexamic acid

Medicine

Placebo

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!