Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages

Stucki, David; Brites, Daniela; Jeljeli, Leïla; Coscollá, Mireia; Liu, Qingyun; Trauner, Andrej; Fenner, Lukas; K. Rutaihwa, Liliana; Borrell, Sònia; Luò, Tāo; Gao, Qian; Kato‐Maeda, Midori; Ballif, Marie; Egger, Matthias; Macedo, Rita; Mardassi, Helmi; Moreno, Milagros; Tudó Vilanova, Griselda; Fyfe, Janet; Globan, Maria; Thomas, Jackson; Jamieson, Frances; L. Guthrie, Jennifer; Asante-Poku, Adwoa; Yeboah‐Manu, Dorothy; M. Wampande, Eddie; Ssengooba, Willy; Joloba, Moses; Henry Boom, W.; Basu, Indira; E. Bower, James; Saraiva, Margarida; Ezídio Gonçalves Vasconcellos, Sidra; Noël Suffys, Philip; Koch, Anastasia; J. Wilkinson, Robert; Bekker, Linda‐Gail; Malla, Bijaya; D. Ley, Serej; Beck, Hans‐Peter; C. de Jong, Bouke; Toit, Kadri; Sánchez-Padilla, Elisabeth; Bonnet, Maryline; Gil-Brusola, Ana; Frank, Matthias; N. Penlap Beng, Véronique; D. Eisenach, Kathleen; AL-Ani, Issam; Ndung’u, Perpetual; Revathi, Gunturu; Gehre, Florian; Akter, Suriya; Ntoumi, Francine; Stewart‐Isherwood, Lynsey; Elias Ntinginya, Nyanda; Rachow, Andrea; Höelscher, Michael; María Cirillo, Daniela; Šķenders, Ģirts; Hoffner, Sven; Bakonytė, Daiva; Stakėnas, Petras; Diel, Roland; Crudu, Valeriu; Moldovan, Olga; Al‐Hajoj, Sahal; Otero, Larissa; Barletta, Francesca; Jane Carter, E.; Diero, Lameck; Supply, Philip; Comas, Iñaki; Niemann, Stefan; Gagneux, Sébastien

doi:10.1038/ng.3704

Public

Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages

Published in Nature Genetics • Oct 31, 2016

Authors:

David Stucki

Daniela Brites

Leïla Jeljeli

Abstract

Sebastien Gagneux and colleagues analyze a global collection of Mycobacterium tuberculosis clinical isolates to classify sublineages by phylogeography. They find globally distributed ‘generalist’ and geographically restricted ‘specialist’ sublineages of lineage 4, indicating that different evolution...

Subject

Generalist and specialist species

Biology

Lineage (genetic)

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!