LTR-mediated retroposition as a mechanism of RNA-based duplication in metazoans

Tan, Shengjun; Cardoso-Moreira, Margarida; Shi, Wenwen; Zhang, Dan; Huang, Jiawei; Mao, Yanan; Jia, Hangxing; Zhang, Yaqiong; Chen, Chunyan; Shao, Yi; Leng, Liang; Liu, Zhonghua; Huang, Xun; Long, Manyuan; E. Zhang, Yong

doi:10.1101/gr.204925.116

Public

LTR-mediated retroposition as a mechanism of RNA-based duplication in metazoans

Published in Genome Research • Oct 20, 2016

Authors:

Shengjun Tan

Margarida Cardoso-Moreira

Wenwen Shi

Abstract

In a broad range of taxa, genes can duplicate through an RNA intermediate in a process mediated by retrotransposons (retroposition). In mammals, L1 retrotransposons drive retroposition, but the elements responsible for retroposition in other animals have yet to be identified. Here, we examined young...

Subject

Biology

Gene duplication

Mechanism (biology)

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