Involvement of mesolimbic dopaminergic network in neuropathic pain relief by treadmill exercise

Wakaizumi, Kenta; Kondo, Takashige; Hamada, Yusuke; Narita, Michiko; Kawabe, Rui; Narita, Hiroki; Watanabe, Moe; Kato, Shigeki; Senba, Emiko; Kobayashi, Kazuto; Kuzumaki, Naoko; Yamanaka, Akihiro; Morisaki, Hiroshi; Narita, Minoru

doi:10.1177/1744806916681567

Public

Involvement of mesolimbic dopaminergic network in neuropathic pain relief by treadmill exercise

Published in Molecular Pain • Jan 1, 2016

Authors:

Kenta Wakaizumi

Takashige Kondo

Yusuke Hamada

Abstract

BACKGROUND: Exercise alleviates pain and it is a central component of treatment strategy for chronic pain in clinical setting. However, little is known about mechanism of this exercise-induced hypoalgesia. The mesolimbic dopaminergic network plays a role in positive emotions to rewards including mot...

Subject

Ventral tegmental area

Nucleus accumbens

Hypoalgesia

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