Nephrotoxicity during Vancomycin Therapy in Combination with Piperacillin-Tazobactam or Cefepime

Cliff Rutter, W.; N. Cox, Jessica; A. Martin, Craig; R. Burgess, Donna; S. Burgess, David

doi:10.1128/aac.02089-16

Public

Nephrotoxicity during Vancomycin Therapy in Combination with Piperacillin-Tazobactam or Cefepime

Published in Antimicrobial Agents and Chemotherapy • Nov 29, 2016

Authors:

W. Cliff Rutter

Jessica N. Cox

Craig A. Martin

Abstract

Recent reports have demonstrated that vancomycin (VAN) may lead to an increase in the incidence of acute kidney injury (AKI) when it is combined with antipseudomonal beta-lactams. This study compared the incidence of AKI associated with VAN plus piperacillin-tazobactam (TZP) or cefepime (FEP). This ...

Subject

Medicine

Cefepime

Acute kidney injury

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