A 3D neurovascular microfluidic model consisting of neurons, astrocytes and cerebral endothelial cells as a blood–brain barrier

Adriani, Giulia; Ma, Dongliang; Pavesi, Andrea; D. Kamm, Roger; L. K. Goh, Eyleen

doi:10.1039/c6lc00638h

Public

A 3D neurovascular microfluidic model consisting of neurons, astrocytes and cerebral endothelial cells as a blood–brain barrier

Published in Lab on a Chip • Dec 8, 2016

Authors:

Giulia Adriani

Dongliang Ma

Andrea Pavesi

Abstract

The neurovascular unit is a complex, interdependent system composed of neurons and neural supporting cells, such as astrocytes, as well as cells that comprise the vascular system including endothelial cells, pericytes, and smooth muscle cells. Each cell type in the neurovascular unit plays an essent...

Subject

Neurovascular bundle

Blood–brain barrier

Microfluidics

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