Colistin Resistance in Carbapenem-Resistant <i>Klebsiella pneumoniae:</i> Laboratory Detection and Impact on Mortality

J. Rojas, Laura; Salim, Madiha; Cober, Eric; S. Richter, Sandra; Perez, Federico; A. Salata, Robert; C. Kalayjian, Robert; R. Watkins, Richard; Marshall, Steve; D. Rudin, Susan; Nicholas Domitrovic, T.; M. Hujer, Andrea; M. Hujer, Kristine; Doi, Yohei; S. Kaye, Keith; Evans, Scott; G. Fowler, Vance; A. Bonomo, Robert; van Duin, David; the Antibacterial Resistance Leadership Group, for

doi:10.1093/cid/ciw805

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Colistin Resistance in Carbapenem-Resistant Klebsiella pneumoniae: Laboratory Detection and Impact on Mortality

Shared by NobleBlocks on Dec 10, 2016 • 12:00 AM UTC

Authors:

Laura J. Rojas

Madiha Salim

Eric Cober

Abstract

Abstract Background. Polymyxins including colistin are an important “last-line” treatment for infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKp). Increasing use of colistin has led to resistance to this cationic antimicrobial peptide. Methods. A cohort nested within the Consortiu...

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