Selective Visualization of the Endogenous Peroxynitrite in an Inflamed Mouse Model by a Mitochondria-Targetable Two-Photon Ratiometric Fluorescent Probe

Cheng, Dan; Pan, Yue; Wang, Lu; Zeng, Zebing; Yuan, Lin; Zhang, Xiaobing; Chang, Young‐Tae

doi:10.1021/jacs.6b10508

Public

Selective Visualization of the Endogenous Peroxynitrite in an Inflamed Mouse Model by a Mitochondria-Targetable Two-Photon Ratiometric Fluorescent Probe

Published in Journal of the American Chemical Society • Dec 5, 2016

Authors:

Dan Cheng

Yue Pan

Lu Wang

Abstract

Peroxynitrite (ONOO – ) is a kind of reactive oxygen species (ROS) with super activity of oxidization and nitration, and overproduction of ONOO – is associated with pathogenesis of many diseases. Thus, accurate detection of ONOO – with high sensitivity and selectivity is imperative for elucidating i...

Subject

Peroxynitrite

Chemistry

Reactive oxygen species

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