Efficacy and safety of adult human bone marrow-derived, cultured, pooled, allogeneic mesenchymal stromal cells (Stempeucel®): preclinical and clinical trial in osteoarthritis of the knee joint

Kumar Gupta, Pawan; Chullikana, Anoop; Rengasamy, Mathiyazhagan; Shetty, Naresh; Pandey, Vivek; Agarwal, Vikas; Wagh, Shrikant; Kulapurathu Vellotare, Prasanth; Damodaran, Devi; Viswanathan, Pachaiyappan; Thej, Charan; Balasubramanian, Sudha; Sen Majumdar, Anish

doi:10.1186/s13075-016-1195-7

Public

Efficacy and safety of adult human bone marrow-derived, cultured, pooled, allogeneic mesenchymal stromal cells (Stempeucel®): preclinical and clinical trial in osteoarthritis of the knee joint

Published in Arthritis Research & Therapy • Dec 1, 2016

Authors:

Pawan Kumar Gupta

Anoop Chullikana

Mathiyazhagan Rengasamy

Abstract

BACKGROUND: Osteoarthritis (OA) is a common and debilitating chronic degenerative disease of the joints. Currently, cell-based therapy is being explored to address the repair of damaged articular cartilage in the knee joint. METHODS: The in vitro differentiation potential of adult human bone marrow-...

Subject

Osteoarthritis

Medicine

Chondrogenesis

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