Standardisation of labial salivary gland histopathology in clinical trials in primary Sjögren's syndrome

A. Fisher, Benjamin; Jonsson, Roland; E. Daniels, Troy; Bombardieri, Michele; M. Brown, Rachel; Morgan, Peter; Bombardieri, Stefano; Ng, Wan‐Fai; G. Tzioufas, Athanasios; Vitali, Claudio; Shirlaw, Pepe; A. Haacke, Erlin; Costa, Sebastian; Bootsma, Hendrika; Devauchelle‐Pensec, Valérie; R. D. J. Radstake, Timothy; Mariette, Xavier; Richards, Andrea; Stack, Rebecca; Bowman, Simon; Barone, Francesca; PP de Albuquerque, Rui; Allen, Rigel; Astorri, Elisa; Baldini, Chiara; Bhabra, Rajdeep; Brito-Zerón, Pilar; Chengot, Preetha; Fedele, Stefano; A Kruize, Aike; Omdal, Roald; Osayi, Kingsley; Porter, Stephen; Potts, John; Poveda-Gallego, Ana; Price, Elizabeth; Priori, Roberta; Ramos-Casals, Manuel; Retamozo, Soledad; Suchak, Krishna; Sutcliffe, Nurhan; Syed, Zahra; R Tappuni, Anwar; Theander, Elke; Wahren-Herlenius, Marie; Triantafyllou, Asterios; Vissink, Arjan; de Vita, Salvatore; Maria della Misericordia, S.

doi:10.1136/annrheumdis-2016-210448

Public

Standardisation of labial salivary gland histopathology in clinical trials in primary Sjögren's syndrome

Published in Annals of the Rheumatic Diseases • Dec 13, 2016

Authors:

Benjamin A. Fisher

Roland Jonsson

Troy E. Daniels

Abstract

Labial salivary gland (LSG) biopsy is used in the classification of primary Sjögren's syndrome (PSS) and in patient stratification in clinical trials. It may also function as a biomarker. The acquisition of tissue and histological interpretation is variable and needs to be standardised for use in cl...

Subject

Medicine

Clinical trial

Histopathology

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